منابع مشابه
Esophageal Cancer and Bisphosphonates
Volume 2 | Issue 1 At the beginning of 2009, Dianne Wysowski of the US Food and Drug Administration summarized 23 reports of esophageal cancer following alendronate use [1]. Wysowski also noted that there had been 31 cases following alendronate use in Europe and Japan and ten cases in which other bisphosphonates had been reported as concomitant or suspect treatment. Median time from exposure to...
متن کاملThe kidney and bisphosphonates.
Bisphosphonates are eliminated from the human body by the kidney. Renal clearance is both by glomerular filtration and proximal tubular secretion. Bisphosphonates given rapidly in high doses in animal models have induced a variety of adverse renal effects, from glomerular sclerosis to acute tubular necrosis. Nevertheless in the doses that are registered for the management of postmenopausal oste...
متن کاملBisphosphonates and glucose homeostasis
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متن کاملBisphosphonates and Bone
Bisphosphonates are pyrophosphate analogues which were used for over a century in industry (mainly in the textile and oil industries) as antiscaling and anticorrosive agents because of their property of inhibition of calcium carbonate precipitation. After the discovery of biological effects of bisphosphonates more than 30 years ago, they have now become indispensable in medicine for the treatme...
متن کاملBisphosphonates and implants
Bisphosphonates are powerful drugs. Their ability to reduce the risk of osteoporotic fractures has saved thousands of people from becoming a fracture patient. Osteoporosis is due to an imbalance in the maintenance remodeling of the skeleton. This remodeling is different from the repair processes following fracture or bone surgery. Because research on the use of bisphosphonates has mostly focuse...
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ژورنال
عنوان ژورنال: Breast Cancer Online
سال: 2005
ISSN: 1470-9031
DOI: 10.1017/s1470903104002676